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Prof. Dr. Jean-Pierre Kinet
Co-founder & CEO

Prof. Dr. Jean-Pierre Kinet

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Background

Jean-Pierre Kinet (b. Oct 23, 1953) is a French-American immunologist recognized for his research on calcium signaling in immune responses. He is Professor of Pathology and an Immunology Faculty Member at Beth Israel Deaconess Medical Center, Harvard Medical School.

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Born in Tilff-Esneux, Belgium, Kinet earned a bachelor’s in Medicine cum laude from the University of Namur and an M.D. from the University of LiĆØge in 1979, where he also completed an internal medicine residency while researching hematology and nephrology.

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In 1982, he joined Henry Metzger’s NIH lab, where he cloned the alpha subunit of the IgE receptor, later identifying the beta and gamma subunits and showing all were required for receptor function. By 1989 he was Head of Molecular Allergy and Immunology at NIAID, leading research into FcεRI gene regulation, antigen recognition, and signal transduction.

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In 1995 he moved to Harvard, where his lab continued FcεRI studies and pioneered work on calcium signaling, identifying key channel proteins in immune and non-neuronal cells.

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Since the 2000s, Kinet has co-founded biotech firms including Astarix and AB Science. He is chairman of VAXON-Biotech, Managing Partner of the €50M iXLife Capital fund, and serves on boards including AB Science SA, Pharmaleads, and ONXEO SA.

Achievements & Honors
Cloned and characterized all three subunits of the IgE receptor, defining its role in allergy and immunity.
Led the Molecular Allergy and Immunology Section at NIAID, advancing FcεRI biology and signaling research.
Appointed Professor of Pathology at Harvard, where his lab uncovered key calcium channels in immune cells.
Co-founded Astarix and AB Science, chairs VAXON-Biotech, and manages the €50M iXLife Capital fund.

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