Is it IBS or the Mammalian Product Allergy?
What is Alpha Gal Syndrome?
Key Differentials
The "Consistently Inconsistent" Symptom Profile
Patients often report that they "ate a burger last week and were fine," but are sick today. This inconsistency is due to co-factors: alcohol, exercise, NSAIDs, and fat content of the meal all dramatically alter the threshold for reaction.
Mammalian Triggers
- Red meat (Beef, Pork, Lamb)
- Dairy (Milk, Cheese)
- Butter & Lard
- Biotech-produced medications
The GI-Only Variant
15%+ of patients have ZERO cutaneous symptoms. No hives, no rash. Only severe abdominal pain, diarrhea, and nausea.
Clinical Pearl
Nocturnal symptoms are a hallmark. If a patient reports waking up sick in the middle of the night after a steak dinner, think Alpha-Gal, not just reflux.
Clinical Identification
The 3 Alpha-Gal Red Flags
Alpha-Gal Syndrome is often a diagnosis of exclusion in GI practice.
Consider FAST-PASE® for these specific cases.
Refractory GI Symptoms
Sleep Disruption
Idiopathic Anaphylaxis
Technical Superiority
Functional Confirmation vs. Static Markers
Why FAST-PASE® is the superior choice for definitive diagnosis.
*BAT relies on patient's own cells, which may be depleted or unresponsive (anergic). FAST-PASE® uses a standardized, immortalized mast cell line for consistent performance.
Resources
Explore trusted resources, research, and insights to better understand Alpha-gal syndrome and its impact.
Frequently Asked Questions
We currently test for the most common food allergens (egg, milk, peanut, and cashew), and the increasingly prevalent red meat allergy caused by the Alpha-gal syndrome. New allergens will be added as the panel expands.
Traditional tests look only at IgE levels or rely on skin exposure, leading to false positives or unclear results. FAST-PASE® measures a cellular response outside of your body, measuring how your blood activates mast cells in response to each allergen, a distinct mechanism from IgE and skin testing, without exposing you to the allergen — all from a simple blood draw.
Most results are ready within a few days. As soon as your sample is analyzed, your report becomes available through the secure portal, and your provider can review it with you.
Yes. FAST-PASE® only requires a small blood sample - no painful skin pricks, no food challenges, and no risk of allergic reactions. It’s the safest choice for both adults and children.
FAST-PASE® measures a cellular response, which is expected to correlate more strongly with true clinical allergy than other tests, as has been published in the clinical utility study. Traditional skin-prick tests have about 50% specificity (essentially a coin flip), while FAST-PASE® provides significantly higher accuracy.
FAST-PASE® will offer insights into reactivity levels in an upcoming update to our test, helping providers understand not only what you’re allergic to, but how strongly.
No insurance is required. FAST-PASE® can be ordered and completed without going through insurance approvals, making the process faster, simpler, and more accessible for families.
Take the test.
Know the truth.
Performance-characterizedvalidated*. Patient-centered.
Safe for children and adults.
